Yet another case where there are too many favorite scenes to pick, so forgive me.
This scene has particular relevence because it's when Joel resigns himself to the memory-erasing procedure and recognizes this will probably be the last flashback he has of Clementine. Heart-breaking and thought-provoking at the same time. We all have had romances end badly and wished that they would be erased forever, but would we still be human without those experiences?